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Immunol Today. 1992 May;13(5):151-3.

Two TNF receptors.

Author information

1
Genentech, South San Francisco, CA 94080.

Abstract

In the past few years, considerable progress has been made on the identification and characterization of tumor necrosis factor (TNF) receptors. The relative roles played by the two receptor types in signaling the diverse functions of TNF are less clear. Here, Louis Tartaglia and David Goeddel summarize progress to date and propose a model of TNF receptor triggering that reconciles the seemingly conflicting data.

PMID:
1322675
DOI:
10.1016/0167-5699(92)90116-O
[Indexed for MEDLINE]

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