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Breast Cancer Res Treat. 1992;21(2):95-100.

Human papillomavirus in breast cancer.

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1
Regina Elena Institute for Cancer Research, CRS, Rome, Italy.

Abstract

Histological sections from paraffin-embedded breast carcinoma and axillary lymph nodes were examined for the presence of human papillomaviruses by two different techniques: the polymerase chain reaction (PCR) and the in situ hybridization with biotin-labelled probes. By PCR we detected HPV 16 DNA sequences in 29.4% of breast tumours and in some metastatic lymph nodes, though we were unable to identify any HPV DNA sequences by in situ hybridization. These results suggest that HPV's could play a role in the genesis of breast neoplasia.

PMID:
1320958
[Indexed for MEDLINE]
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