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J Hypertens. 1992 Mar;10(3):287-98.

A factorial study of salt restriction and a low-fat/high-fibre diet in hypertensive subjects.

Author information

1
University Department of Medicine, Royal Perth Hospital, Western Australia.

Abstract

OBJECTIVE:

To compare the independent and additive effects of sodium restriction and a low-fat, high polyunsaturated: saturated fatty acids (P:S) ratio, high-fibre diet upon blood pressure.

DESIGN:

A randomized, parallet, double-blind, placebo-controlled (for sodium) 2 x 2 factorial trial.

SETTING:

Clinical.

PARTICIPANTS:

Ninety-five hypertensive subjects (mean blood pressure, 137/83 mmHg), mean age 53.5 years, consuming less than 30 ml ethanol/day were selected from community volunteers. Seventy-nine treated and twelve untreated hypertensives completed the trial.

INTERVENTION:

Subjects followed either a low-sodium, low-fat/high-fibre diet (less than 60 mmol sodium/day; 30% fat energy; P:S ratio = 1; 30-50 g fibre/day) or a low-sodium, normal-fat/normal-fibre diet (less than 60 mmol sodium/day; 40% fat energy; P:S ratio = 0.3; 15 g fibre/day) for 8 weeks. Half of each group received 100 mmol/day NaCl and the remainder received placebo.

MAIN OUTCOME MEASURES:

Blood pressure and blood lipids.

RESULTS:

Sodium restriction significantly reduced standing and supine systolic blood pressure, with no effect upon diastolic blood pressure. The low-fat/high-fibre diet had no effect upon blood pressure, but significantly reduced total cholesterol, low-density lipoprotein cholesterol and high-density lipoprotein cholesterol.

CONCLUSIONS:

Sodium restriction reduced blood pressure and did not raise low-density lipoprotein cholesterol. A low-fat/high-fibre diet did not reduce blood pressure but lowered cholesterol levels. A combination of the two regimes has the greater potential for reducing cardiovascular risk in hypertensives.

PMID:
1315827
[Indexed for MEDLINE]

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