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Ophthalmology. 2003 Sep;110(9):1822-6.

Trabeculectomy with beta radiation: long-term follow-up.

Author information

1
Department of Ophthalmology, United Christian Hospital, Kowloon, Hong Kong.

Abstract

PURPOSE:

To evaluate the long-term outcome and complications of trabeculectomy with beta radiation.

DESIGN:

Retrospective noncomparative case series.

PARTICIPANTS:

Forty-three patients with confirmed primary open-angle glaucoma (POAG), who received trabeculectomy with adjunctive beta radiation at the Prince of Wales Hospital between June 1991 and November 1994.

METHODS:

Patients fulfilling the preceding criteria were followed up longitudinally. The visual acuity, intraocular pressure (IOP), bleb morphology, and complications were evaluated.

MAIN OUTCOME MEASURES:

Visual acuity, IOP, bleb morphology, complications.

RESULTS:

Forty-three eyes of 43 consecutive Chinese patients were recruited and successfully followed up for a minimum of 7 years. The mean age +/- 1 standard deviation (SD) was 60.9 +/- 13.0 years. There were 29 males and 14 females. The mean baseline IOP +/- 1 SD was 28.3 +/- 5.8 mmHg. The mean postoperative IOP +/- 1 SD after the initial trabeculectomy was 11.9 +/- 4.3 mmHg, and the mean number of preoperative IOP-lowering eyedrops +/- 1 SD was reduced from 2.8 +/- 0.5 to 0.7 +/- 1.0 at 7 years follow-up. The qualified success rate at 7 years follow-up, defined as IOP <or=21 mmHg with and without medication(s), was 88.4%. The complete success rate at 7 years defined as IOP <or=21 mmHg without medication was 60.7%. Two eyes developed blebitis, and one of them progressed to corneal decompensation after the infection. One eye had hypotony, and one eye had a traumatic ruptured bleb. Twelve eyes (27.9%) developed significant cataract. No corneal ulceration or scleral necrosis was encountered.

CONCLUSIONS:

From this noncomparative study, trabeculectomy with a single dose of 1000 rad beta radiation used as an adjunctive measure for POAG in Chinese eyes had achieved a qualified success rate of 88.4% at 7 years.

PMID:
13129883
DOI:
10.1016/S0161-6420(03)00561-X
[Indexed for MEDLINE]

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