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Am J Med Genet. 1992 Jan 1;42(1):61-7.

Head circumference of children with Down syndrome (0-36 months)

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Department of Industrial Engineering, University of Wisconsin-Madison.

Erratum in

  • Am J Med Genet 1992 Jul 1;43(4):768.


This study provides statistically appropriate head circumference reference curves for males and females with Down syndrome (DS) from birth to 36 months of age. A total of 239 males and 182 females from five study populations, yielding a combination of cross-sectional and longitudinal data, were used for the analysis. The method of least squares was used to test the fit of the growth model y = a+bx+c[log(x + 1)], where x is age in months. These standardized curves should provide information of value in the medical, physical, and developmental management of children with DS.

[Indexed for MEDLINE]

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