Monoclonal gammopathy in systemic lupus erythematosus

Lupus. 1992 Aug;1(4):263-4. doi: 10.1177/096120339200100410.

Abstract

In order to ascertain the incidence of monoclonal gammopathy (MG) in systemic lupus erythematosus (SLE), 120 SLE patients were evaluated. Four patients (3.3%), two of whom were under 50 years of age, were found to have a monoclonal immunoglobulin in their serum. Our data agree with the previous literature in demonstrating a higher incidence of MG in SLE patients in comparison with the general population. Neither the clinical importance nor the pathogenetic significance of this association is known.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Female
  • Humans
  • Immunoglobulin G / blood
  • Immunoglobulin M / blood
  • Immunoglobulin kappa-Chains / blood
  • Lupus Erythematosus, Systemic / complications*
  • Lupus Erythematosus, Systemic / immunology
  • Male
  • Middle Aged
  • Paraproteinemias / complications*
  • Paraproteinemias / immunology

Substances

  • Immunoglobulin G
  • Immunoglobulin M
  • Immunoglobulin kappa-Chains