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Nat Rev Immunol. 2003 Aug;3(8):677-85.

Ebola virus: from discovery to vaccine.

Author information

1
Department of Medical Microbiology, University of Manitoba, Winnipeg, Canada. heinz_feldmann@hc-sc.gc.ca

Abstract

Ebola virus, being highly pathogenic for humans and non-human primates and the subject of former weapons programmes, is now one of the most feared pathogens worldwide. In addition, the lack of pre- and post-exposure interventions makes the development of rapid diagnostics, new antiviral agents and protective vaccines a priority for many nations. Further insight into the ecology, immunology and pathogenesis of Ebola virus will promote the delivery of these urgently required tools.

PMID:
12974482
DOI:
10.1038/nri1154
[Indexed for MEDLINE]

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