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Cad Saude Publica. 2003 Jul-Aug;19(4):1189-93. Epub 2003 Sep 8.

[Pragmatic clinical trials: an option in the construction of health-related evidence].

[Article in Portuguese]

Author information

1
Departamento de Epidemiologia e Métodos Quantitativos em Saúde, Escola Nacional de Saúde Pública, Fundação Oswaldo Cruz, Rio de Janeiro, RJ, 21041-210, Brasil. evandro@ensp.fiocruz.br

Abstract

The authors present and discuss the potential of pragmatic clinical trials as an alternative to both explanatory trials and observational studies to support the use of therapeutic interventions with good evidence. They argue that this strategy, when properly applied, can be a powerful tool to obtain unbiased measures of effectiveness, with simpler logistics and lower costs than in current clinical trials.

PMID:
12973582
DOI:
10.1590/s0102-311x2003000400039
[Indexed for MEDLINE]
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