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Am J Cardiol. 2003 Sep 15;92(6):711-2.

Effect of simvastatin versus placebo on treadmill exercise time until the onset of intermittent claudication in older patients with peripheral arterial disease at six months and at one year after treatment.

Author information

1
Department of Medicine, Cardiology Division, Westchester Medical Center/New York Medical College, Macy Pavilion Room 138, Valhalla, NY 10595, USA. WSAronow@aol.com

Abstract

Simvastatin significantly increased treadmill exercise time until onset of intermittent claudication from baseline by 54 seconds (a 24% increase, p <0.0001) at 6 months after treatment and by 95 seconds (a 42% increase, p <0.0001) at 1 year after treatment. At 6 months and 1 year after treatment with placebo, treadmill exercise time until onset of intermittent claudication was not significantly different from baseline exercise time.

PMID:
12972114
[Indexed for MEDLINE]

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