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Emerg Infect Dis. 2003 Aug;9(8):999-1002.

NmcA carbapenem-hydrolyzing enzyme in Enterobacter cloacae in North America.

Author information

1
University of Washington School of Medicine, Seattle, Washington, USA.

Erratum in

  • Emerg Infect Dis. 2003 Sep;9(9):1188.

Abstract

An imipenem-resistant Enterobacter cloacae isolate was recovered from the blood of a patient with a hematologic malignancy. Analytical isoelectric focusing, inhibitor studies, hydrolysis, induction assays, and molecular sequencing methods confirmed the presence of a NmcA carbapenem-hydrolyzing enzyme. This first report of NmcA detected in North America warrants further investigation into its distribution and clinical impact.

PMID:
12967501
PMCID:
PMC3020613
DOI:
10.3201/eid0908.030096
[Indexed for MEDLINE]
Free PMC Article

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