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Clin Infect Dis. 2003 Sep 15;37(6):841-5. Epub 2003 Aug 28.

Infections due to Haemophilus influenzae serotype E: microbiological, clinical, and epidemiological features.

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Centro Nacional de Microbiología, Instituto de Salud Carlos III, Ministry of Health, Majadahonda, Madrid, Spain.


Surveillance after introduction of Haemophilus influenzae serotype b vaccination in Spain identified 26 H. influenzae serotype e (HiE) isolates. Of these, 16 (61.5%) were recovered from patients aged >16 years and 10 (38.5%) from children <16 years of age. HiE caused respiratory infections in 14 patients (9 with pneumonia), conjunctivitis in 4, vaginitis in 2, abscess in 2, and cellulitis, peritoneal infection, sepsis and meningitis in 1 patient each. HiE was strongly clonal and highly resistant to ampicillin and cotrimoxazole, and the incidence of HiE infection did not increase over time.

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