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J Clin Invest. 2003 Sep;112(5):648-51.

Dendritic cells and the intestinal bacterial flora: a role for localized mucosal immune responses.

Author information

1
Sir William Dunn School of Pathology, University of Oxford, Oxford, United Kingdom.

Abstract

Mammals coexist in an overall symbiotic relationship with a complex array of commensal bacterial flora that colonizes the gastrointestinal tract. These intestinal bacteria interface with cells of the mucosal immune system, including DCs. Here we discuss mechanisms of interaction between intestinal bacteria and DCs and the role of localized gastrointestinal immune responses.

PMID:
12952911
PMCID:
PMC182213
DOI:
10.1172/JCI19545
[Indexed for MEDLINE]
Free PMC Article
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