Sympathetic ophthalmia associated with ocular and cerebral vasculitis: an angiographic and radiologic study

Eur J Ophthalmol. 2003 Jul;13(6):584-7. doi: 10.1177/112067210301300614.

Abstract

Purpose: To describe a case of sympathetic ophthalmia (SO) associated with ocular and cerebral vasculitis.

Methods: The authors report a 38-year-old woman who presented with bilateral uveitis 7 years after a penetrating trauma to the right eye. Ocular examination included fundus fluorescein and indocyanine green angiography. Medical history disclosed an episode of dysarthria and right-sided weakness.

Results: Anterior uveitis was present in the previously injured pseudophakic right eye, which harbored a piece of glass stuck in the lower temporal iris. In the left eye, vitreal inflammation with retinal sheathing and subretinal lesions was predominant. Besides retinal vasculitis, fundus angiography showed choroidal vasculitis. Neurologic studies were compatible with cerebral vasculitis.

Conclusions: In SO, choroidal vasculitis that is invisible clinically can be demonstrated angiographically. Although rare, inflammation can also affect the nervous system.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Choroid / blood supply
  • Cyclosporine / therapeutic use
  • Female
  • Fluorescein Angiography
  • Humans
  • Immunosuppressive Agents / therapeutic use
  • Indocyanine Green
  • Magnetic Resonance Imaging
  • Ophthalmia, Sympathetic / complications*
  • Ophthalmia, Sympathetic / diagnosis
  • Ophthalmia, Sympathetic / drug therapy
  • Prednisone / therapeutic use
  • Retinal Vasculitis / diagnosis
  • Retinal Vasculitis / drug therapy
  • Retinal Vasculitis / etiology*
  • Treatment Outcome
  • Vasculitis / diagnosis
  • Vasculitis / drug therapy
  • Vasculitis / etiology
  • Vasculitis, Central Nervous System / diagnosis
  • Vasculitis, Central Nervous System / drug therapy
  • Vasculitis, Central Nervous System / etiology*
  • Visual Acuity

Substances

  • Immunosuppressive Agents
  • Cyclosporine
  • Indocyanine Green
  • Prednisone