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Am J Psychiatry. 2003 Sep;160(9):1691-3.

High blood monocyte counts and neopterin levels in children with autistic disorder.

Author information

1
Department of Psychiatry, Indiana University School of Medicine, 1111 West 10th Street, Indianapolis, IN 46202-4800, USA.

Abstract

OBJECTIVE:

Leukocyte counts and plasma neopterin levels were determined in autistic children and matched healthy comparison subjects.

METHOD:

Blood from 31 autistic children and 28 age- and gender-matched healthy comparison subjects was analyzed for numbers of neutrophils, eosinophils, basophils, lymphocytes, monocytes, and total leukocytes and for plasma neopterin levels.

RESULTS:

The monocyte count and neopterin level were significantly higher in the autistic children than in the comparison subjects.

CONCLUSIONS:

These results suggest that the immune system may be activated in some children with autism.

PMID:
12944347
DOI:
10.1176/appi.ajp.160.9.1691
[Indexed for MEDLINE]

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