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Am J Orthop (Belle Mead NJ). 2003 Aug;32(8):402-4.

Aspergillus infection after total knee arthroplasty.

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Department of Orthopaedics, Clinical Outcome Research Center, Health Services Research and Policy School of Public Health, University of Minnesota, Minneapolis, USA.


The literature includes little information about the treatment protocol for Aspergillus infection after total knee arthroplasty. In this article, we describe the case of a nonimmunocompromised patient who lacked predisposing risk factors and who initially presented with aseptic loosening of a total knee prosthesis that postoperatively had grown Aspergillus niger. Intraoperative culture and frozen-section results for the pseudocapsule were negative. Two days postoperatively, culture results showed heavy growth of A niger. The patient was treated with a 6-week course of amphotericin B followed by oral antifungal therapy. She was doing well and had no symptoms 12 months after surgery.

[Indexed for MEDLINE]

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