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Behav Neurosci. 2003 Aug;117(4):825-32.

Wheel access duration in rats: II. Day-night and within-session changes.

Author information

1
Department of Psychology, Wilfrid Laurier University, Waterloo, Ontario, Canada. reikelbo@wlu.ca

Abstract

Time of day and duration of wheel access were manipulated to see how running changed over days. Young male rats were given 2 hr of wheel access, during either the light or dark phase. Over 24 days, running increased 4-fold in the dark group but remained low and stable in the light group. With rats given either 1 or 4 hr of dark phase wheel access, running increased much more in the 4-hr group (even in Hour 1) than in the 1-hr group. The within-session running pattern for high runners changed from a habituation to a sensitization profile. Running and cocaine self-administration (S. H. Ahmed & G. F. Koob, 1998, 1999) are affected similarly by session length, suggesting running as an interesting addiction model.

PMID:
12931966
DOI:
10.1037/0735-7044.117.4.825
[Indexed for MEDLINE]

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