Format

Send to

Choose Destination
Breast Cancer Res. 2003;5(5):R110-3. Epub 2003 Jun 5.

Breast cancer in association with thyroid disorders.

Author information

1
GATA Haydarpasa Training Hospital, Medical Oncology Department, KadIkoy, Istanbul, Turkey. oturken@hotmail.com

Abstract

BACKGROUND:

The relationship between breast cancer and thyroid diseases is controversial. Discrepant results have been reported in the literature. The incidences of autoimmune and nonautoimmune thyroid diseases were investigated in patients with breast cancer and age-matched control individuals without breast or thyroid disease.

METHODS:

Clinical and ultrasound evaluation of thyroid gland, determination of serum thyroid hormone and antibody levels, and fine-needle aspiration of thyroid gland were performed in 150 breast cancer patients and 100 control individuals.

RESULTS:

The mean values for anti-thyroid peroxidase antibodies were significantly higher in breast cancer patients than in control individuals (P = 0.030). The incidences of autoimmune and nonautoimmune thyroid diseases were higher in breast cancer patients than in control individuals (38% versus 17%, P = 0.001; 26% versus 9%, P = 0.001, respectively).

CONCLUSION:

Our results indicate an increased prevalence of autoimmune and nonautoimmune thyroid diseases in breast cancer patients.

Comment in

PMID:
12927040
PMCID:
PMC314421
DOI:
10.1186/bcr609
[Indexed for MEDLINE]
Free PMC Article

Supplemental Content

Full text links

Icon for BioMed Central Icon for PubMed Central
Loading ...
Support Center