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Epilepsia. 2003;44 Suppl 7:26-9.

Assessing the efficacy of antiepileptic treatments: the ketogenic diet.

Author information

1
Pediatric Epilepsy Service, Departments of Neurology and Pediatrics, Massachusetts General Hospital, Boston, Massachusetts 02115, USA. ethiele@partners.org

Abstract

PURPOSE:

To evaluate the evidence for determining if the ketogenic diet is an effective treatment for epilepsy.

METHODS:

A literature review of published data over the past 80 years concerning the ketogenic diet was performed, focusing on efficacy, tolerability, age of patient population, as well as study design.

RESULTS:

There have been several studies involving prospective and retrospective studies showing the ketogenic diet to be a very efficacious treatment in epilepsy, particularly epilepsy in childhood. However, no Class 1 studies have been published concerning the efficacy of the ketogenic diet.

CONCLUSIONS:

The ketogenic diet appears to be a very effective treatment for epilepsy, particularly in childhood. It would be beneficial to have Class 1 studies available to help better define the role of the diet both in children and adults.

PMID:
12919336
DOI:
10.1046/j.1528-1157.44.s7.4.x
[Indexed for MEDLINE]
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