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Kardiol Pol. 2002 Oct;57(10):332-6.

Anthocyanins--an adjunct to cardiovascular therapy?

[Article in English, Polish]

Author information

1
Department of Pharmacology, Basic Sciences Institute, Military Medical Academy, Łódź, Poland.

Abstract

BACKGROUND:

Anthocyanins are one of the most important water-soluble plant pigments. They belong to flavonoids and are derivatives of 2-phenylo-benzo-gamma pyren. They have antioxidant and anti-inflammatory properties and, therefore, may be potentially used to combat oxidative stress, frequently present in cardiovascular diseases.

AIM:

To assess the effects of anthocyanins from chokeberry (Aronia Melanocarpa) on some parameters of oxidation-reduction balance in an animal model.

METHODS:

Of 20 male Wistar rats, 10 received for 3 months pure water, and the other rats 10-100 mg/l of anthocyanins from Aronia melanocarpa. Afterwards, blood samples were collected for assessment of the (1) content of substances reacting with thiobarbitural--TBARS, (2) antioxidant status and glutathione peroxidase activity, (3) concentration of sulphydryl groups, and (4) nitrite concentration.

RESULTS:

Anthocyanins significantly reduced the content of TBARS and thiol protein groups and non-significantly increased glutathione peroxidase activity, total content of antioxidants and nitrite concentration.

CONCLUSIONS:

Anthocyanins from chokeberry decrease lipid peroxidation which may be potentially used to combat oxidative stress.

PMID:
12917728

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