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Gene Expr Patterns. 2003 Aug;3(4):413-7.

Sox15 is up regulated in the embryonic mouse testis.

Author information

  • 1Department of Paediatrics, Centre for Hormone Research, Murdoch Children's Research Institute, Royal Children's Hospital, University of Melbourne, Melbourne, Vic 3052, Australia.

Erratum in

  • Gene Expr Patterns. 2003 Dec;3(6):785.


The mammalian sex determining region on the Y chromosome, SRY, is the founding member of the SOX gene family. SOX genes share a common DNA-binding motif termed the HMG box and have diverse roles in vertebrate embryonic development and tissue differentiation. Sox15 expression was analysed during mouse embryogenesis by whole-mount in situ hybridisation and Real Time RT-PCR. Sox15 was found to be expressed in developing mouse gonads from 11.5 dpc to 13.5 dpc with a peak of expression at 12.5 dpc. Expression was approximately twice as high in the male gonad as in the female gonad.

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