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Bioinformatics. 2003 Aug 12;19(12):1585-6.

ClustalW-MPI: ClustalW analysis using distributed and parallel computing.

Author information

1
Bioinformatics Institute, 30 Medical Drive, Singapore 117609, Republic of Singapore. kuobin@bii.a-star.edu.sg

Abstract

ClustalW is a tool for aligning multiple protein or nucleotide sequences. The alignment is achieved via three steps: pairwise alignment, guide-tree generation and progressive alignment. ClustalW-MPI is a distributed and parallel implementation of ClustalW. All three steps have been parallelized to reduce the execution time. The software uses a message-passing library called MPI (Message Passing Interface) and runs on distributed workstation clusters as well as on traditional parallel computers.

PMID:
12912844
DOI:
10.1093/bioinformatics/btg192
[Indexed for MEDLINE]

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