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J Clin Microbiol. 2003 Aug;41(8):3915-8.

Molecular epidemiology of Haemophilus influenzae type b isolated from children with clinical cases of conjugate vaccine failures.

Author information

  • 1Centro Nacional de Microbiología, Instituto de Salud Carlos III, Ministry of Health, Madrid, Spain. jcampos@iscii.es

Abstract

We analyzed eight invasive Haemophilus influenzae strains isolated from individual children vaccinated appropriately for their ages. Five of the strains were type b and three were nontypeable strains. Children infected with nontypeable strains had a protective level of anti-H. influenzae type b antibodies, while only one of the children whose cases represented true vaccine failure did.

PMID:
12904417
PMCID:
PMC179828
[PubMed - indexed for MEDLINE]
Free PMC Article
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