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Curr Opin Cell Biol. 2003 Aug;15(4):389-95.

Lipids and the exocytotic machinery of eukaryotic cells.

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Department of Cell and Developmental Biology, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599-7090, USA.


The molecular machines that drive protein transport through the secretory pathway function exert their activities on the surfaces of membrane bilayers. It is now clear that the various lipid components of these bilayers play direct and versatile roles in modulating the activity of proteins that either themselves constitute core components of the membrane trafficking machinery, or represent proteins that regulate such core components.

[Indexed for MEDLINE]

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