Abstract
The aim of this report was to evaluate late left ventricular function in survivors of Wilms' tumor and to compare patients treated with anthracyclines with those treated without anthracycline and with normal subjects. Wilms' tumor survivors treated without anthracycline had no myocardial abnormalities. A large percentage of patients treated with anthracycline presented with increased end-systolic wall stress. Results indicate that there is a high incidence of subclinical cardiovascular abnormalities in such patients.
Publication types
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Clinical Trial
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Comparative Study
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Controlled Clinical Trial
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Research Support, Non-U.S. Gov't
MeSH terms
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Adolescent
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Adult
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Anthracyclines / therapeutic use*
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Body Weights and Measures
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Cardiac Volume / physiology
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Child
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Child, Preschool
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Echocardiography*
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Female
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Follow-Up Studies
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Heart Ventricles / diagnostic imaging*
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Humans
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Kidney Neoplasms / diagnostic imaging
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Kidney Neoplasms / drug therapy*
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Male
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Reference Values
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Survivors
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Treatment Outcome
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Ventricular Function, Left / drug effects*
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Wilms Tumor / diagnostic imaging
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Wilms Tumor / drug therapy*