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Genes Brain Behav. 2002 Jan;1(1):9-13.

The fallacy of behavioral phenotyping without standardisation.

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Cognitive Neurobiology, Institute for Anatomy II, University of Köln, Joseph Stelzmann Str., Cologne, Germany.


Behavioral phenotyping of mutant mice is a new and challenging task for the behavioral neuroscientist. Therefore, standardisation of the experimental conditions is required to permit comparisons between the results of experiments within and between laboratories. Once mutation-induced behavioral changes have been identified, phenotyping of mouse mutants should be performed along a systematic trajectory, which allows for an in-depth characterisation of the mutant under investigation.

[Indexed for MEDLINE]

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