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Pediatr Infect Dis J. 2003 Jul;22(7):659-61.

Immunologic memory with no detectable bactericidal antibody response to a first dose of meningococcal serogroup C conjugate vaccine at four years.

Author information

1
Oxford Vaccine Group, Department of Paediatrics, John Radcliffe Hospital, Headington, UK. jodie.mcvernon@imm.ox.ac.uk

Abstract

Fourteen children with no detectable bactericidal antibody response to a first dose of meningococcal C conjugate vaccine at 4 years of age were given a booster dose of the same vaccine 2 years later. A rapid 1000-fold rise in postimmunization bactericidal antibody titers, a measured either 7 or 14 days later, suggested previous immunologic priming.

PMID:
12886896
[Indexed for MEDLINE]

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