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Paediatr Respir Rev. 2003 Sep;4(3):172-7.

Respiratory virus infections in cystic fibrosis.

Author information

1
Cystic Fibrosis/Respiratory Unit, Department of Child Health, University Hospital of Wales, CF14 4XW, Cardiff, UK.

Abstract

Respiratory virus infections have pronounced and long-lasting effects on patients with cystic fibrosis (CF), resulting in significant declines in FVC, FEV(1) and Shwachman score, significantly increasing both the frequency and duration of hospitalisation. Deleterious effects on patients with CF have been reported for most viruses studied but the effects of respiratory syncytial virus and influenza appear the greatest. There is circumstantial evidence that respiratory virus infections may facilitate bacterial infections, particularly Pseudomonas aeruginosa.

PMID:
12880751
DOI:
10.1016/s1526-0542(03)00059-9
[Indexed for MEDLINE]

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