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Curr Opin Plant Biol. 2003 Aug;6(4):365-71.

The salicylic acid loop in plant defense.

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Division of Biology, and The Molecular, Cellular and Developmental Biology Program, 303 Ackert Hall, Kansas State University, 66506-4901, Manhattan, Kansas, USA.


Salicylic acid is an important signal molecule in plant defense. In the past two years, significant progress has been made in understanding the mechanism of salicylic-acid biosynthesis and signaling in plants. A pathway similar to that found in some bacteria synthesizes salicylic acid from chorismate via isochorismate. Salicylic-acid signaling is mediated by at least two mechanisms, one requiring the NON-EXPRESSOR OF PR1 (NPR1) gene and a second that is independent of NPR1. Feedback loops involving salicylic acid modulate upstream signals. These feedback loops may provide a point for integrating developmental, environmental and other defense-associated signals, and thus fine-tune the defense responses of plants.

[Indexed for MEDLINE]

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