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Org Lett. 2003 Jul 24;5(15):2715-7.

Simple one-flask method for the preparation of hydroxamic acids.

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1
Dipartimento di Chimica, Università degli Studi di Sassari, via Vienna 2, I-07100 Sassari, Italy. ggp@uniss.it

Abstract

[reaction: see text] A one-step conversion of carboxylic acids to hydroxamic acids under very mild conditions is described. This simple and efficient method has been applied for the synthesis of enantiopure hydroxamate of alpha-amino acids and peptides.

PMID:
12868897
DOI:
10.1021/ol034903j
[Indexed for MEDLINE]
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