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J Bacteriol. 2003 Aug;185(15):4630-7.

A 65-kilobase pathogenicity island is unique to Philadelphia-1 strains of Legionella pneumophila.

Author information

1
Department of Microbiology and Immunology, Dalhousie University, Halifax, Nova Scotia, Canada B3H 4H7.

Abstract

Nucleotide sequence analysis of an approximately 80-kb genomic region revealed an approximately 65-kb locus that bears hallmarks of a pathogenicity island. This locus includes homologues of a type IV secretion system, mobile genetic elements, and known virulence factors. Comparative studies with other Legionella pneumophila strains and serogroups indicated that this approximately 65-kb locus is unique to L. pneumophila serogroup 1 Philadelphia-1 strains.

PMID:
12867476
PMCID:
PMC165780
[Indexed for MEDLINE]
Free PMC Article

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