[Surgical treatment of pulmonary aspergillosis]

Kyobu Geka. 2003 Jul;56(7):519-24; discussion 525-7.
[Article in Japanese]

Abstract

We studied clinically upon 10 surgical cases of pulmonary aspergillosis. There were 7 male and 3 female cases, and the median age was 59 years. Seven cases had underlying bronchopulmonary diseases, and 9 cases had underlying diseases including systemic diseases, such as diabetes mellitus. There were 3 wedge resections, and 6 lobectomies, and 1 two-staged surgery (cavernostomy + muscle transposition). Eight cases whose lesion extended beyond neither chest wall nor mediastinal pleura were treated successfully by pulmonary resections almost within one lobectomy. One case, who had a cavitary lesion and multiple patchy infiltrates in the other lobes, cured by lobectomy including a main cavitary lesion and postoperative treatment with an antifungal agent. All cases returned home almost uneventfully, but 1 case of two-staged surgery died at home suddenly of massive hemoptysis. Surgical treatments of pulmonary aspergillosis are recommended when the lesions can be resected completely, that is, when patients are relatively well, lesions extend beyond neither chest wall nor hilar bronchus or vessels, and when the lungs other than the lesions are not extensively destroyed.

Publication types

  • Case Reports
  • English Abstract

MeSH terms

  • Adult
  • Aged
  • Antifungal Agents / administration & dosage
  • Aspergillosis / drug therapy
  • Aspergillosis / surgery*
  • Diabetes Complications
  • Female
  • Humans
  • Lung Diseases, Fungal / drug therapy
  • Lung Diseases, Fungal / surgery*
  • Male
  • Middle Aged
  • Pneumonectomy / methods
  • Postoperative Care

Substances

  • Antifungal Agents