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Sci Aging Knowledge Environ. 2003 Jan 8;2003(1):VP1.

An engineer's approach to the development of real anti-aging medicine.

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Department of Genetics, University of Cambridge, Downing Street, Cambridge CB2 3EH, UK.


In this Viewpoint, I list the various age-related molecular and cellular changes that are thought to limit mammalian life-span, and I outline a problem-solving approach to reversing these detrimental changes. This approach should help to prevent the development of these age-related changes into life-threatening pathologies and possibly, in due course, allow a large increase in healthy human life expectancy.

[Indexed for MEDLINE]

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