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Genome Biol. 2003;4(7):403. Epub 2003 Jun 18.

EST analyses predict the existence of a population of chimeric microRNA precursor-mRNA transcripts expressed in normal human and mouse tissues.

Abstract

A significant population of expressed sequence tags (ESTs) encodes chimeric transcripts containing microRNA (miRNA) precursor sequences as well as pieces of adjacent mRNAs in sense orientation. These chimeric transcripts may potentially be involved in miRNA biosynthesis, and/or affect expression of adjacent mammalian mRNAs.

PMID:
12844357
PMCID:
PMC193628
DOI:
10.1186/gb-2003-4-7-403
[Indexed for MEDLINE]
Free PMC Article

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