Format

Send to

Choose Destination
See comment in PubMed Commons below
Ann Pharmacother. 2003 Jul-Aug;37(7-8):1124-7.

Isotretinoin and psychiatric illness in adolescents and young adults.

Author information

1
Division of Pharmacy Practice, St. Louis College of Pharmacy, St. Louis, MO 63110-1088, USA. senders@stlcop.edu

Abstract

OBJECTIVE:

To evaluate the relationship between isotretinoin and psychiatric illness in adolescents and young adults.

DATA SOURCES:

Primary literature located via MEDLINE (1966-December 2002). Key terms were isotretinoin, depression, psychosis, suicide, and adolescents.

DATA SYNTHESIS:

Information regarding depression was added to isotretinoin labeling in 1998 following a series of case reports and submitted to the MedWatch system.

CONCLUSIONS:

Although a causal relationship may exist between isotretinoin and psychiatric illness in adolescents and young adults, this has not been demonstrated in the literature. Until evidence establishes a presence or lack of causality, prescribers should exercise caution when treating adolescents and young adults with isotretinoin.

PMID:
12841827
DOI:
10.1345/aph.1C415
[Indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Atypon
    Loading ...
    Support Center