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Appl Environ Microbiol. 2003 Jul;69(7):4268-71.

Complement resistance is essential for colonization of the digestive tract of Hirudo medicinalis by Aeromonas strains.

Author information

1
Institute for Infectious Diseases, University of Berne, CH-3010 Berne, Switzerland.

Abstract

From the crop of the medicinal leech, Hirudo medicinalis, only Aeromonas veronii bv. sobria can be cultured consistently. Serum-sensitive A. veronii mutants were unable to colonize H. medicinalis, indicating the importance of the mammalian complement system for this unusual simplicity. Complementation of one selected mutant restored its ability to colonize. Serum-sensitive mutants are the first mutant class with a colonization defect for this symbiosis.

PMID:
12839811
PMCID:
PMC165153
[Indexed for MEDLINE]
Free PMC Article

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