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Trends Cell Biol. 2003 Jul;13(7):386-92.

Function and regulation of Ena/VASP proteins.

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  • 1Massachusetts Institute of Technology, Cambridge, MA 02139, USA.


Regulation of cytoskeletal dynamics is required to coordinate cell movement, adhesion and shape change. The Ena/VASP protein family is thought to play an important role in linking signaling pathways to remodeling of the actin cytoskeleton. This review will examine the mechanisms by which Ena/VASP function might control actin dynamics and how these proteins are linked to various signaling pathways.

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