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Fetal Diagn Ther. 2003 Jul-Aug;18(4):223-5.

Veno-occlusive disease in a fetus caused by pyrrolizidine alkaloids of food origin.

Author information

1
Department of Obstetrics and Gynaecology, Albert-Ludwigs-University, Freiburg, Germany. rrase@frk.ukl.uni-freiburg.de

Abstract

We report the occurrence of veno-occlusive disease in a preterm neonate who was symptomatic with hepatomegaly and ascites and was delivered by caesarean section for threatening fetal asphyxia and died shortly afterwards. Post mortem examination revealed veno-occlusive disease typical for pyrrolizidine alkaloid poisoning. The content of pyrrolizidine alkaloids in the liver could be confirmed. Analysis of a herbal mixture which was used for cooking in the family revealed high amounts of the respective alkaloids clarifying the source of the poison and the causal relationship.

PMID:
12835579
DOI:
10.1159/000070799
[Indexed for MEDLINE]

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