Send to

Choose Destination
See comment in PubMed Commons below
Bioinformatics. 2003 Jul 1;19(10):1300-1.

HaploBlockFinder: haplotype block analyses.

Author information

Center for Genome Information, Department of Environmental Health, University of Cincinnati, Cincinnati, OH 45267, USA.


Recent studies have unveiled discrete block-like structures of linkage disequilibrium (LD) in the human genome. We have developed a set of computer programs to analyze the block-like LD structures (haplotype blocks) based on haplotype data. Three definitions of haplotype block are supported, including minimal LD range, no historic recombination, and chromosome coverage. Tagged SNPs that uniquely distinguish common haplotypes are identified. A greedy algorithm was used to improve the efficiency. Two separate utilities were also provided to assist visual inspection of haplotype block structure and pattern of linkage disequilibrium.


A web interface for the HaploBlockFinder is available at the source codes are also freely available on the web site.

[Indexed for MEDLINE]
PubMed Commons home

PubMed Commons

How to join PubMed Commons

    Supplemental Content

    Loading ...
    Support Center