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Int J Obes Relat Metab Disord. 2003 Jun;27(6):669-76.

Longitudinal changes in weight in perimenopausal and early postmenopausal women: effects of dietary energy intake, energy expenditure, dietary calcium intake and hormone replacement therapy.

Author information

1
Department of Medicine and Therapeutics, University of Aberdeen, Medical School Buildings, Foresterhill, Aberdeen, UK. h.macdonald@abdn.ac.uk

Abstract

OBJECTIVE:

To investigate whether energy intake or energy expenditure affects 5-7 y weight gain in perimenopausal and early postmenopausal women, and whether hormone replacement therapy (HRT) use or dietary calcium (Ca) intake are contributory factors.

DESIGN:

Longitudinal, observational study of healthy women around the menopause.

SUBJECTS:

A total of 1064 initially premenopausal women, selected from a random population of 5119 women aged 45-54 y at baseline. In all, 907 women (85.2%) returned 6.3+/-0.6 y later for repeat measurements. Of these, 36% were postmenopausal (no HRT) and 45% had taken HRT, and 898 women completed the questionnaires.

MEASUREMENTS:

Weight, height, estimation of energy intake by food frequency questionnaire and physical activity level (PAL) by questionnaire.

RESULTS:

Change in PAL influenced weight change explaining 4.4% (P=0.001) of the variation. Alterations in dietary energy intake also had a small but significant effect (0.6% P=0.013). Dietary Ca intake had no effect on weight or weight change.

CONCLUSION:

Mean weight had increased and was influenced more by reduced energy expenditure rather than increased energy intake. HRT and dietary Ca intake did not influence weight gain.

PMID:
12833110
DOI:
10.1038/sj.ijo.0802283
[Indexed for MEDLINE]

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