Format

Send to

Choose Destination
Infect Control Hosp Epidemiol. 2003 Jun;24(6):422-6.

Spread of methicillin-resistant Staphylococcus aureus (MRSA) among household contacts of individuals with nosocomially acquired MRSA.

Author information

1
Department of Internal Medicine, University of Virginia Health System, Charlottesville, Virginia 22908, USA.

Abstract

OBJECTIVE:

To determine the frequency with which methicillin-resistant Staphylococcus aureus (MRSA) is spread from colonized or infected patients to their household and community contacts.

DESIGN:

Retrospective cohort study.

SETTING:

University hospital.

PARTICIPANTS:

Household and community contacts of MRSA-colonized or -infected patients for whom MRSA screening cultures were performed.

RESULTS:

MRSA was isolated from 25 (14.5%) of 172 individuals. Among the contacts of index patients who had at least one MRSA-colonized contact, those with close contact to the index patient were 7.5 times more likely to be colonized (53% vs 7%; 95% confidence interval, 1.1 to 50.3; P = .002). An analysis of antimicrobial susceptibility and DNA fingerprint patterns suggested person-to-person spread.

CONCLUSIONS:

MRSA colonization occurs frequently among household and community contacts of patients with nosocomially acquired MRSA, suggesting that transmission of nosocomially acquired MRSA outside of the healthcare setting may be a substantial source of MRSA colonization and infection in the community.

PMID:
12828318
DOI:
10.1086/502225
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Cambridge University Press
Loading ...
Support Center