The proteasome--an emerging therapeutic target in cancer

N Engl J Med. 2003 Jun 26;348(26):2597-8. doi: 10.1056/NEJMp030092.
No abstract available

Publication types

  • Comment

MeSH terms

  • Antineoplastic Agents / therapeutic use*
  • Boronic Acids / therapeutic use*
  • Bortezomib
  • Humans
  • Multiple Myeloma / drug therapy*
  • NF-kappa B / metabolism*
  • Peptide Hydrolases / drug effects*
  • Phosphorylation
  • Protease Inhibitors / therapeutic use*
  • Proteasome Endopeptidase Complex*
  • Pyrazines / therapeutic use*

Substances

  • Antineoplastic Agents
  • Boronic Acids
  • NF-kappa B
  • Protease Inhibitors
  • Pyrazines
  • Bortezomib
  • Peptide Hydrolases
  • Proteasome Endopeptidase Complex
  • ATP dependent 26S protease