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Trends Microbiol. 2003 Jun;11(6):264-71.

Plant and animal rhabdovirus host range: a bug's view.

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Department of Entomology, 120 Thorne Hall, The Ohio State University-OARDC, 1680 Madison Avenue, Wooster, OH 44691, USA.


Rhabdoviruses affect human health, terrestrial and aquatic livestock and crops. Most rhabdoviruses are transmitted by insects to their vertebrate or plant hosts. For insect transmission to occur, rhabdoviruses must negotiate barriers to acquisition, replication, movement, escape and inoculation. A better understanding of the molecular interactions of rhabdoviruses with insects will clarify the complexities of rhabdovirus infection processes and epidemiology. A unique opportunity for studying how insects become hosts and vectors of rhabdoviruses is provided by five maize-infecting rhabdoviruses that are differentially transmitted by one or more related species of two divergent homopteran families.

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