Format

Send to

Choose Destination
Genome Res. 2003 Jun;13(6B):1395-401.

Analysis of the mouse transcriptome for genes involved in the function of the nervous system.

Author information

1
Department of Neurobiology, Harvard Medical School, Boston, Massachusetts 02115, USA. gustinci@sissa.it

Abstract

We analyzed the mouse Representative Transcript and Protein Set for molecules involved in brain function. We found full-length cDNAs of many known brain genes and discovered new members of known brain gene families, including Family 3 G-protein coupled receptors, voltage-gated channels, and connexins. We also identified previously unknown candidates for secreted neuroactive molecules. The existence of a large number of unique brain ESTs suggests an additional molecular complexity that remains to be explored.A list of genes containing CAG stretches in the coding region represents a first step in the potential identification of candidates for hereditary neurological disorders.

PMID:
12819138
PMCID:
PMC403671
DOI:
10.1101/gr.1135303
[Indexed for MEDLINE]
Free PMC Article

Supplemental Content

Full text links

Icon for HighWire Icon for PubMed Central
Loading ...
Support Center