Format

Send to

Choose Destination
Immunol Today. 1992 Sep;13(9):362-7.

Group A streptococcal M proteins: virulence factors and protective antigens.

Author information

1
Dept of Immunology, Medical School, University of Newcastle upon Tyne, UK.

Abstract

Rebecca Lancefield described group A streptococcal M proteins over 50 years ago, and they have remained at the forefront of investigations into streptococcal pathogenicity to the present day. As described in this review, they form cell surface fibrils with several functions, ranging from resisting phagocytosis and inducing host-crossreactive antibodies, to presenting the host immune system with an accessible protective antigen.

PMID:
1281632
DOI:
10.1016/0167-5699(92)90173-5
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center