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J Cell Physiol. 2003 Aug;196(2):219-23.

cDNA array technology in melanoma: an overview.

Author information

1
Regina Elena Cancer Institute, CRS, Via delle Messi d'Oro, Rome, Italy.

Abstract

Genetic aberrations, mostly resulting in changes in gene expression, are critical events in cancer onset and progression. The advent of the cDNA array technology allows the screening and the efficient measurement of expression of thousands genes simultaneously in a wide spectrum of experimental and clinical models. This genomic scale approach is being currently used to obtain global views of human cancer gene expression and to identify genetic markers that might be important for diagnosis, prognosis, and therapy. This review discusses some recent findings obtained by means of cDNA arrays investigating the human melanoma.

PMID:
12811814
DOI:
10.1002/jcp.10255
[Indexed for MEDLINE]

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