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Thromb Res. 1992 Jul 1;67(1):41-8.

Effect of sodium pentosan polysulphate on the thrombogenicity of prothrombin complex concentrates.

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1
Institute of Pharmacology and Toxicology, Medical Academy Erfurt, FRG.

Abstract

The addition of pentosan polysulphate sodium (NaPPS) to thrombogenic prothrombin complex concentrates (PCC) dose-dependently reduces or abolishes thrombus formation in rats in the stasis model acc. to Wessler. However, no reduction of thrombogenicity was found in PCC preparations manufactured in the presence of NaPPS.

PMID:
1279834
[Indexed for MEDLINE]

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