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J Infect Dis. 2003 Jun 15;187 Suppl 2:S327-34.

Drosophila melanogaster antimicrobial defense.

Author information

1
Institut de Biologie Mol├ęculaire et Cellulaire, UPR9022 du Centre National de la Recherche Scientifique, Strasbourg, France.

Abstract

The Drosophila melanogaster host defense is complex but remarkably efficient. It is a multifaceted response to a variety of fungal, bacterial, and parasitic invaders. Current knowledge is discussed on recognition of infectious microorganisms and on the activation of intracellular signaling cascades that concur with the expression of numerous immune-responsive genes, among which, to date, the most prominent appear to encode potent antimicrobial peptides.

PMID:
12792847
DOI:
10.1086/374758
[Indexed for MEDLINE]

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