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Cell. 2003 May 30;113(5):551-2.

Nanog: a new recruit to the embryonic stem cell orchestra.

Author information

1
University of Pennsylvania, School of Veterinary Medicine, Center for Animal Transgenesis and Germ Cell Research, New Bolton Center, 382 West Street Road, Kennett Square, PA 19348, USA.

Abstract

In this issue of Cell, and add a new transcriptional operating system to the known Oct4 and Stat3 systems required for early embryonal stem cell potency and self-renewal. Nanog, a homeobox transcription factor, plays a crucial role in the second embryonic cell fate specification following formation of the blastocyst.

PMID:
12787492
DOI:
10.1016/s0092-8674(03)00394-5
[Indexed for MEDLINE]
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