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Biosci Biotechnol Biochem. 2003 Apr;67(4):803-8.

Relationship between response to and production of the aerial mycelium-inducing substances pamamycin-607 and A-factor.

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1
Department of Applied Biological Science, Tokyo University of Agriculture and Technology, Saiwai-cho, Fuchu, Tokyo 183-8509, Japan.

Abstract

Respectively, exogenous pamamycin-607 and A-factor restored or stimulated aerial mycelium formation in 30 (67%) and 6 (13%) of 45 Streptomyces strains, and both restored or stimulated it in 5 strains (11%). Pamamycin-607 production was detected in 3 of those strains that responded to pamamycin-607. These findings indicate that pamamycin-607 acts on the common regulatory system for aerial mycelium formation in Streptomyces spp. but is not a universal autoregulator. Increased or decreased antibacterial production occurred in 5 strains in association with aerial mycelium formation by pamamycin-607 or A-factor.

PMID:
12784621
DOI:
10.1271/bbb.67.803
[Indexed for MEDLINE]
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