Format

Send to

Choose Destination
See comment in PubMed Commons below
Int Arch Occup Environ Health. 2003 Jul;76(6):424-30. Epub 2003 Jun 3.

Metabolic disturbances in male workers with rotating three-shift work. Results of the WOLF study.

Author information

1
Occupational Medicine, Department of Public Health and Clinical Medicine, University of Umeå, 901 85 Umeå, Sweden.bernt.karlsson@vll.se

Abstract

OBJECTIVES:

The aim of the present study was to investigate the relationship between important metabolic risk factors for coronary heart disease (CHD) and type 2 diabetes in shift workers and day workers.

METHODS:

Cross-sectional data from a sub-population in the WOLF study consisting of 665 day workers and 659 three-shift workers in two plants were analysed.

RESULTS:

A higher proportion of shift workers than day workers had high triglyceride levels (> or =1.7 mmol/l), low levels of HDL-cholesterol (<0.9 mmol/l) and abdominal obesity (waist/hip ratio>0.9). The risk of low HDL-cholesterol was doubled in shift workers, (odds ratio (OR): 2.02, 95% confidence interval (95% CI): 1.24-3.28) after being adjusted for age, socio-economic factors, physical activity, current smoking, social support and job strain. High levels of triglycerides were also significantly associated with shift work (OR: 1.40, 95% CI: 1.08-1.83). The OR for abdominal obesity was 1.19, (95% CI: 0.92-1.56). The prevalence of hyperglycaemia (serum glucose > or =7.0 mmol/l) was similar in day and shift workers. No significant interaction was seen between shift work and abdominal obesity with regard to the associations with triglycerides and HDL-cholesterol.

CONCLUSIONS:

We found a significant association between shift work and lipid disturbances (i.e. low HDL-cholesterol and high triglyceride levels). We did not find any association with hyperglycaemia.

PMID:
12783235
DOI:
10.1007/s00420-003-0440-y
[Indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Springer
    Loading ...
    Support Center